Senior Director, Payer Accounts

Since our founding in 2009, REGENXBIO has pioneered what’s possible in gene therapy. Today, we are advancing a pipeline of gene therapies designed to improve the lives of patients facing serious rare and retinal diseases and preparing to bring innovative new medicines to patients.
Our work is fueled by purpose and urgency because every day matters to patients and their families. At REGENXBIO, you’ll find meaningful opportunities to grow, collaborate, and contribute to the advancement of potentially transformative gene therapies. Together, our talented team is working to make a meaningful difference for patients and their families.
What we do matters.

The Opportunity
The Senior Director, Payer Accounts will play a critical role in ensuring patient access to REGENXBIO’s gene therapy portfolio by leading strategic engagement with key national and regional payers, PBM, and GPO accounts. This role is accountable for developing, negotiating, and executing market access strategies that secure timely and sustainable reimbursement while building long-term, trusted partnerships with payer decision-makers. As a member of the Market Access organization, the Senior Director Payer Accounts will collaborate closely with Market Access, Trade, Commercial Enablement, Marketing, HEOR, and Legal teams to align account strategies with brand and access objectives.

How You’ll Contribute
Build and oversee the national and payer account teams. Develop and execute strategic account plans for national and regional payers, PBMs, specialty pharmacies, and IDNs to achieve optimal coverage and reimbursement for REGENXBIO’s therapies. Serve as the primary point of contact and business owner for assigned payer accounts, ensuring alignment of objectives, proactive issue resolution, and consistent communication. Establish and maintain senior-level relationships with key payer stakeholders (e.g., VP of Pharmacy, Medical Directors, Contracting Executives, Clinical Policy leads). Lead contract strategy and negotiations, including value-based and innovative access models, aligned with corporate and brand goals. Analyze payer policies, utilization trends, and competitive dynamics to identify opportunities and anticipate potential access barriers. Monitor contract performance and compliance, providing actionable insights and recommendations to Market Access leadership. Translate data-driven insights into strategic recommendations, leveraging internal analytics to communicate REGENXBIO’s differentiated value proposition. Collaborate cross-functionally with Market Access, Trade, Commercial Enablement, Marketing, HEOR, and Sales to develop and execute pull-through initiatives supporting patient access. Support the development of coverage education tools, reimbursement resources, AMCP dossier, PIE material and payer-facing value materials in collaboration with internal stakeholders. Partner with Medical, Legal, and Compliance to ensure all payer engagements and materials adhere to regulatory and ethical standards. Provide market intelligence to inform national access planning and support leadership decision-making. Travel up to 50–60% of the time, including overnight travel, is required It is imperative that REGENXBIO employees embody our core values by working collaboratively, building strong relationships and using clear communication to meet shared objectives.

What You’ll Bring
We are looking for someone who thrives in a collaborative, patient-focused environment with the following skills: Bachelor’s degree required; advanced degree (MBA, MPH, or equivalent) preferred. 12+ years of recent experience in the biopharmaceutical industry, including 5+ years in national or regional payer account management roles and 3+ years in leadership roles managing national or regional account teams. Strong expertise in rare diseases and/or gene therapies, with a strong understanding of the U.S. payer landscape, including commercial payers, Medicare, Medicaid, integrated delivery networks, market access, and reimbursement. Demonstrated success developing and executing payer strategies for high-cost specialty products especially for gene therapies and rare disease products. Demonstrated success in contract negotiation, formulary access, and strategic account planning within specialty, Gene therapy, rare disease, or high-cost therapy categories. Experience with value-based contracting, alternative reimbursement models, or innovative access solutions strongly preferred. Strong business and clinical acumen with the ability to connect therapeutic value to payer priorities. Proven ability to influence and engage senior stakeholders, both externally with payers and internally across functions. Proven ability to navigate complex cross-functional environments and influence internal and external stakeholders. Excellent presentation, analytical, and communication skills; adept at translating data into clear strategic insights. Strong leadership, coaching, and communication skills with the ability to navigate complexity and ambiguity. High integrity, adaptability, team-player and collaborative mindset, with a patient- focused approach and comfort working in a dynamic, small-company environment, aligned with REGENXBIO’s core values. Ability to travel up to 50–60%, including overnight travel.

What You Can Expect
At REGENXBIO, we're committed to fostering an environment where people can do meaningful work, grow professionally, and make an impact. Our core values - trust, accountability, perseverance, and innovation - drive everything we do. We offer a comprehensive and competitive benefit and compensation package that includes market-competitive salaries, an annual bonus program, education assistance, paid caregiver leave, a retirement plan with employer match, stock options at all levels, summer hours, and more. The estimated compensation range for this role is $245,000 - $350,000 annually. The actual salary offered to the final candidate depends on factors such as relevant work experience, skills, education, and years of experience.